Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester
Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester
CAS: 203854-49-3
Molecular Formula: C25H29NO6
Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester - Names and Identifiers
| Name | Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester |
| Synonyms | Fmoc-β-HoGlu(OtBu)-OH FMOC-BETA-HOGLU(OTBU)-OH FMOC-GLU(OTBU)-(C*CH2)OH FMOC-BETA-HOMOGLU(OTBU)-OH Fmoc-β-homoglutamic acid(OtBu) FMOC-L-BETA-HOMOGLUTAMIC ACID(OTBU) Fmoc-L-beta-homoglutamic acid(OtBu) Fmoc-L-β-homoglutamic acid 6-tert-butyl ester Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester FMOC-L-BETA-HOMOGLUTAMIC ACID 6-TERT-BUTYL ESTER FMOC-L-BETA-HOMOGLUTAMIC ACID DELTA-T-BUTYL ESTER 6-tert-butoxy-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-6-oxohexanoic acid (3S)-6-tert-butoxy-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-6-oxohexanoic acid (3S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid |
| CAS | 203854-49-3 |
| InChI | InChI=1/C25H29NO6/c1-25(2,3)32-23(29)13-12-16(14-22(27)28)26-24(30)31-15-21-19-10-6-4-8-17(19)18-9-5-7-11-20(18)21/h4-11,16,21H,12-15H2,1-3H3,(H,26,30)(H,27,28) |
| InChIKey | XPCDWOCHPTYDPV-INIZCTEOSA-N |
Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester - Physico-chemical Properties
| Molecular Formula | C25H29NO6 |
| Molar Mass | 439.5 |
| Density | 1.214±0.06 g/cm3(Predicted) |
| Melting Point | 115-120℃ |
| Boling Point | 638.8±50.0 °C(Predicted) |
| Flash Point | 340.2°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 3.4E-17mmHg at 25°C |
| BRN | 8019724 |
| pKa | 4.31±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.566 |
Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester - Introduction
Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester is an organic compound with the following properties:
1. Properties: Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester is a solid, soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane. It is usually in the form of a powder.
2. Use: Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester is a reagent for protecting amino acids, commonly used in solid phase synthesis of peptides and proteins. It can prepare various synthetic peptides by chemical synthesis method.
3. Preparation method: the preparation of Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester is generally obtained by esterification of L-β-high glutamic acid with tert-butanol. The resulting product was then reacted with 2,4, 5-trimethylphenyldinitropropyl ester (Fmoc-OSu) to give Finally the Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester.
4. Safety information: When using and operating the Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester, care should be taken to prevent inhalation, swallowing, and contact with skin, eyes, etc. Personal protective equipment such as protective gloves, goggles and laboratory coats should be worn. In case of accidental inhalation or skin contact, rinse immediately with water and seek medical help.
1. Properties: Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester is a solid, soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane. It is usually in the form of a powder.
2. Use: Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester is a reagent for protecting amino acids, commonly used in solid phase synthesis of peptides and proteins. It can prepare various synthetic peptides by chemical synthesis method.
3. Preparation method: the preparation of Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester is generally obtained by esterification of L-β-high glutamic acid with tert-butanol. The resulting product was then reacted with 2,4, 5-trimethylphenyldinitropropyl ester (Fmoc-OSu) to give Finally the Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester.
4. Safety information: When using and operating the Fmoc-L-beta-homoglutamic acid 6-tert-butyl ester, care should be taken to prevent inhalation, swallowing, and contact with skin, eyes, etc. Personal protective equipment such as protective gloves, goggles and laboratory coats should be worn. In case of accidental inhalation or skin contact, rinse immediately with water and seek medical help.
Last Update：2024-04-09 15:17:54
